extract.peakROI(mzML, ionpairs,
    tolerance = "ppm:20",
    timeWindowSize = 5,
    baselineQuantile = 0.65,
    integratorTicks = 5000,
    peakAreaMethod = NetPeakSum,
    angleThreshold = 5,
    peakwidth = "8,30",
    rtshift = NULL,
    bsplineDensity = 100,
    bsplineDegree = 2,
    sn.threshold = 3,
    TPAFactors = NULL);